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KMID : 0861020060210030055
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Korea Journal of Herbology
2006 Volume.21 No. 3 p.55 ~ p.67
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The Effects of Artemisiae Capillaris, Ponciri Fructus and Cartaegi Fructus in Obese Rats Induced by High Fat Diet
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Ban Sang-Seok
Yoon Hyeon-Deok
Shin Oh-Chul
Shin Yoo-Jung
Park Chi-Sang
Park Ji-Ha
Seo Bu-Il
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Abstract
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Objectives : This study was designed in order to determine the effects of Artemisiae Capillaris, Ponciri Fructus and Cartaegi Fructus so as to care the obesity and obesity-related diabetes.
Methods : After induction of obesity by high fat-diet in rats, the each extracts of three medicinal stuffs were administrated with continuous high fat-diet for 4 weeks. And the changes of lipid metabolism, liver function and blood levels of glucose and insulin were examined.
Results : Blood concentrations of triglyceride, free fatty acid and LDL-cholestrol were increased in obese group compared with standard dieted group. By treatment of Ponciri Fructus or Cartaegi Fructus with high fat-diet, their concentrations of glyceride and free fatty acid were significantly decreased. Blood level of LDL -cholesterol was decreased in all stuffs treated groups, however atherogenic index was significantly decreased in treatment of Cartaegi Fructus with high fat-dieted group.
Conclusion : High fat-dieted with treatment of Ponciri Fructus or Cartaegi Fructus, fatty degeneration was remarkably diminished.
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KEYWORD
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Artemisiae Capillaris, Ponciri Fructus, Cataegi Fructus, obesity, obesity-related diabetes
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